Identification of N'-methyl-4-pyridone-3-carboxamide in human plasma.
نویسندگان
چکیده
After the oral administration of nicotinamide to human subjects, two ultraviolet-absorbing compounds have regularly been detected on chromatograms of plasma extracts. The less polar of these, named Compound Y, has been identified as N’-methyl2-pyridone-5-carboxamide (1). In the present communication, evidence is presented that the more polar metabolite, Compound X, is N’-methyl-4-pyridone-3-carboxamide.1
منابع مشابه
N-Methyl-4-pyridone-5-carboxamide as a metabolite of nicotinic acid in man and monkey.
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ورودعنوان ژورنال:
- The Journal of biological chemistry
دوره 238 شماره
صفحات -
تاریخ انتشار 1963